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Kisspeptin

$84.99

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Product Description

Kisspeptin-5 is a short-chain peptide fragment derived from the larger kisspeptin protein family, widely studied for its interaction with reproductive signaling pathways and neuroendocrine communication. In laboratory settings, Kisspeptin-5 has been researched for its role in hypothalamic signaling and its potential influence on gonadotropin-releasing hormone (GnRH) activity.

This compound has gained attention in preclinical and experimental research focused on hormonal signaling, reproductive biology, metabolic communication, and neuroendocrine regulation. Due to its compact structure, Kisspeptin-5 is often explored as a simplified research analogue for studying receptor interaction and peptide signaling mechanisms.

Research Use Only. Not for human consumption, therapeutic use, or diagnostic purposes.

Researchers select Kisspeptin for studies involving reproductive signaling and peptide-receptor interactions because of its targeted activity within the Kisspeptin signaling pathway. Areas of interest often include:

  • Investigation of hypothalamic-pituitary-gonadal (HPG) axis communication

  • GnRH signaling pathway research

  • Neuroendocrine and reproductive hormone studies

  • Peptide receptor binding and activation models

  • Fertility and puberty-related signaling mechanisms

  • Hormonal feedback loop analysis

  • Metabolic and endocrine interaction research

Its smaller peptide chain also makes it attractive for receptor-specific laboratory models and mechanistic studies

Neuroendocrine Signaling

Kisspeptin peptides are commonly researched for their interaction with neuroendocrine pathways involved in hormonal regulation and signaling cascades.

Reproductive Biology

Studies frequently examine kisspeptin signaling in relation to reproductive hormone release, puberty initiation pathways, and fertility-associated mechanisms.

GnRH Activation Research

Kisspeptin compounds are widely associated with laboratory research into gonadotropin-releasing hormone secretion and hypothalamic communication.

Receptor Interaction Studies

Kisspeptin-5 is used in peptide-receptor binding investigations to better understand signaling specificity and downstream cellular responses.

Metabolic & Endocrine Communication

Emerging research explores possible interactions between kisspeptin signaling and metabolic regulation pathways

  1. Kotani M, et al. The metastasis suppressor gene KiSS-1 encodes kisspeptins, the natural ligands of the orphan G protein-coupled receptor GPR54. Journal of Biological Chemistry (2001).

  2. Seminara SB, et al. The GPR54 gene as a regulator of puberty. New England Journal of Medicine (2003).

  3. Messager S, et al. Kisspeptin directly stimulates gonadotropin-releasing hormone release via G protein-coupled receptor 54. Proceedings of the National Academy of Sciences (2005).

  4. Pinilla L, et al. Kisspeptins and reproduction: physiological roles and regulatory mechanisms. Physiological Reviews (2012).

  5. Oakley AE, et al. Kisspeptin signaling in the brain. Endocrine Reviews (2009).