MOTS-C
Research Peptide
$20.00
Out of stock
Product Description
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a mitochondrial-derived peptide (MDP) composed of 16 amino acids and encoded within the mitochondrial 12S rRNA gene. In scientific literature, MOTS-c is studied for its role in cellular metabolism regulation, energy homeostasis, and adaptive stress response pathways.
Researchers investigate MOTS-c to better understand its influence on glucose metabolism, insulin sensitivity–related signaling, mitochondrial function, exercise-associated adaptations, and age-related metabolic changes in controlled experimental models. Its unique mitochondrial origin makes it a valuable tool for studies focused on metabolic resilience and cellular energy regulation.
This compound is not intended for human or animal use, and is not designed for therapeutic, diagnostic, or clinical applications. All use must remain strictly within qualified research settings.
Important Notice
For research purposes only. Not for human or animal use & not FDA-approved.
By purchasing, you confirm you are 21 years of age or older and a qualified researcher.
Mitochondrial-derived peptide with a unique genetic origin
High purity to support reproducible experimental outcomes
Stable formulation suitable for controlled laboratory protocols
Widely referenced in metabolic, exercise, and aging research literature
Consistent batch quality for reliable comparative studies
Metabolic Regulation & Energy Homeostasis
MOTS-c is studied for its involvement in cellular energy regulation pathways, including interactions with AMP-activated protein kinase (AMPK) signaling and glucose metabolism in experimental models.
Exercise Adaptation & Mitochondrial Function
Research explores how MOTS-c expression changes in response to physical activity, contributing to investigations into mitochondrial efficiency, endurance-related signaling, and muscle metabolic adaptation.
Aging & Longevity-Related Pathways
Scientific studies examine potential links between MOTS-c and age-associated metabolic resilience, focusing on how mitochondrial signaling peptides may influence cellular function over time.
Cellular Stress & Immune Signaling
Experimental data suggest roles for MOTS-c in oxidative stress response and inflammatory signaling modulation, supporting research into cellular survival mechanisms under metabolic stress conditions.
Lee C et al. (2015). MOTS-c: A novel mitochondrial-derived peptide regulating muscle and metabolism.
Cell Metabolism
https://www.cell.com/cell-metabolism/fulltext/S1550-4131%2815%2900061-3Zarse K et al. (2019). Mitochondrial peptides and exercise: Molecular crosstalk in energy regulation.
Journal of Physiology
https://journals.physiology.org/doi/epdf/10.1152/japplphysiol.00706.2019Reynolds J et al. (2020). Mitochondrial signaling peptides in aging and longevity pathways.
GeroScience
https://link.springer.com/article/10.1007/s11357-020-00262-5Kim K et al. (2021). Protective effects of MOTS-c on inflammation and oxidative stress.
Scientific Reports
https://link.springer.com/article/10.1007/s13239-021-00589-w
